To me Pedigrees look like family trees. Well...thats basically what they are. The official description is pedigrees are used to show family histories of certain diseases. The three ways diseases can be passed through a family are:
- Autosomal Dominant
- Autosomal Recessive
- Sex Linked
Autosomal dominant means that one parent has a gene with the disease and the other parent doesn't. The chance that each child will get this disease is 50-50. If there is an infected person then that means one of their parents was infected also. Autosomal dominant diseases show up in every generation. Males and females are each likely to be infected.
What kind of inheritance pattern is demonstrated in this pedigree? How do you know? Give an example of a human disease that is inherited this way.
My answer was partially right. I said it was autosomal dominant. I knew this because the disease did not skip a generation. I had no idea about what diseases could be inherited this way though. Now I found out that some diseases that are dominant are Tuberous Sclerosis, Myotonic Dystrophy, Huntington's disease, Achondroplasia, and Neurofibromatosis.
Another Autosomal Dominant Pedigree:
Autosomal recessive disease means that two copies of an abnormal gene must be present for a disease to be passed on. This gives each child, born to parents that each have an autosomal recessive gene, a 25% chance risk of being infected with the disease. There is a 50% chance of a child inheriting one abnormal gene, which would make the child a carrier. (FACT: The child that is born with to abnormal genes does not mean they will be infected with the gene. It means they have a risk of being infected.) Both sexes are equally affected.
Another Autosomal Recessive Pedigree:
Sex Linked can also be described as X linked. This refers to very few recessive genes that reside on the X chromosome. Men are mainly affected by sex linked diseases. If a father has a disease he will pass it on to his daughter. The daughter then becomes a carrier. Her sons have a 50% chance of getting the disease.
The question on the quiz was the same as the first two. Except my answer was autosomal recessive, when it actually is Sex Linked. I still didn't know and diseases. Now I know some Sex Linked diseases are color blindness, Hunter's disease, Fabry's disease, and menkes disease.
Another example of a Sex Linked Pedigree:
Well I have learned a lot about Pedigrees and I hope this shows it! Stay tuned for a blog about Eugenics! It is coming I promise! hahah
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